Pharma Grade

Letrozole is the name of a chemical that is a 3rd generation selective aromatase inhibitor. Femara is an anti-cancer medicine. Many forms of breast cancer cells are stimulated by oestrogens, so by limiting their amount you can stop the growth of the cancer. The advantage of Femara is blocking the production of estrogens, and not inhibiting their action, as in the case of Nolvadex. Letrozole is a very effective substance. Even a daily dose of 1 tablet (2.5 mg of letrozole) can reduce estrogen production by over 80%. This medicine is only used in postmenopausal women with advanced hormone-receptor positive breast cancer.

Femara, used in doping by men, is a drug that offers a very positive effect. It protects much better against excess estrogens, and thus side effects, than the combination of Nolvadex and Proviron. As little as 0.5 mg a day helps to virtually eliminate unwanted, typically estrogenic side effects. The use of letrozole during therapy with the use of strong aromatizing androgens, such as Dianabol or Testosterone, helps to effectively protect against possible water retention and gynecomastia. According to research, given in a dose of 0.5 mg and 2.5 mg, it reduced the concentration of estrone by 80.8-82.0%, oestradiol by 68.1-84.1% and 71%, over 0.5 mg of letrozole daily is able to lower the level of estrone below detection. The activity of the aromatase enzyme is able to reduce by 98.4-98.9%. The studies also showed an increase in the secretion of LH, FSH, SHGB, which directly translates into an increase in the level of androgens. It can be used to raise androgen levels to PCT, but SERMs are better suited for several reasons, but not entirely inadequate. It raises IGF-1 secretions by up to 24% and it is the only non-steroidal IA that works in this way. How does letrozole compare to arimidex and aromasin? I have come across opinions that the effectiveness in inhibiting aromatase and its activity exceeds both substances 10-20 times! This compound has a long half-life of up to 4 days, so the start-up period is quite long. The maximum reduction in estrogen is noted 48-78 hours from the last administration. In order to achieve an equal blood concentration, it must be taken for about 60 days.
Interestingly, it turns out that letrozole can inhibit, reverse and reduce existing gynecomastia with great efficiency. The studies carried out on mice showed significant effectiveness in the treatment of the existing enlarged glands and the complete reversal of the lesions.